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This spinoff may be acetylated, hydroxylated and glucuronidated. Cytochrome P-450 together with CYP3A, might Participate in a significant purpose in clonazepam reduction and oxidation. The elimination fifty percent-lifetime of clonazepam is typically 30 to 40 several hours. Clonazepam pharmacokinetics are dose-impartial all through the dosing range